Why Your Brain Craves PQQ

Analysis by Dr. Joseph Mercola
December 02, 2019

 Story at-a-glance

• Pyrroloquinoline quinone (PQQ) is particularly important for the health and protection of your mitochondria. It also helps regenerate new mitochondria
• PQQ has been shown to improve the function of beta amyloid-damaged brain cells — a hallmark of Alzheimer’s disease — and prevent the formation of alpha-synclein proteins associated with Parkinson’s disease. It can even help prevent neuronal cell death in cases of traumatic brain injury
• Studies show PQQ improves mental processing and memory. It also works synergistically with CoQ10, producing better results than either of these nutrients alone
• PQQ lowers C-reactive protein and interleukin-6, which are inflammatory biomarkers, and upregulates Nrf2 expression — a biological hormetic that upregulates beneficial intercellular antioxidants
• PQQ has also been shown to boost the activity of primary life span extension transcriptional factors, which led the researchers to surmise that PQQ may play a role in longevity

While your diet is one of the most important tools you can use to take control of your health, certain supplements can be helpful, especially when it comes to improving your mitochondrial function. One particularly powerful supplement in this regard is pyrroloquinoline quinone (PQQ),¹ which has been shown to promote the growth of new mitochondria (mitochondrial biogenesis).

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